Guanidine thiocyanate is a powerful reagent widely used in molecular biology protocols for efficient nucleic acid isolation. It irreversibly inactivates DNase and RNase enzymes, protecting RNA and DNA from degradation during cell lysis. As a chaotropic agent, guanidine thiocyanate also disrupts hydrogen bonding and weakens intramolecular forces within proteins and macromolecules, enhancing solubility and facilitating the removal of unwanted cellular debris. This dual functionality makes it ideal for use in high-yield extraction workflows.
Assay: ≥99.5%
CAS Number | 593-84-0 |
---|---|
Store At Temperature | Room temperature, tightly closed container |
Shipping Condition | Room temperature |
Guanidine thiocyanate is a powerful reagent widely used in molecular biology protocols for efficient nucleic acid isolation. It irreversibly inactivates DNase and RNase enzymes, protecting RNA and DNA from degradation during cell lysis. As a chaotropic agent, guanidine thiocyanate also disrupts hydrogen bonding and weakens intramolecular forces within proteins and macromolecules, enhancing solubility and facilitating the removal of unwanted cellular debris. This dual functionality makes it ideal for use in high-yield extraction workflows.
Assay: ≥99.5%
CAS Number | 593-84-0 |
---|---|
Store At Temperature | Room temperature, tightly closed container |
Shipping Condition | Room temperature |