Description
Polyethylenimine “Max” (PEI MAX®) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both in vitro and in vivo transfection. PEI MAX® has a high density of protonatable amino groups, with amino nitrogen as every third atom. This imparts a high buffering ability at nearly any pH. Hence, once inside the endosome, PEI MAX® disrupts the vacuole and releases the genetic material into the cytoplasm. Stable complexation with DNA, efficient entry into the cell, and ability to escape the endosome makes PEI MAX® a highly efficient transfection reagent which is compatible for a wide range of cell lines/types including the most commonly used HEK293 and CHO cells grown in adherent and suspension cultures. PEI MAX® is capable of yielding high efficiency cell lines without compromising cell viability compared to other PEI and liposomal transfection reagents available in the market.
Key Benefits
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Superior Performance
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High transfection efficiency with low cytotoxicity compared to other reagents on the market, suitable for use in larger concentrations and in sensitive cells.
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Low cytotoxicity
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Even at higher concentrations, PEI MAX® minimizes cellular disruption.
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High Quality
- Made in the USA
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Flexible Workflow
- Easy to optimize and introduce into application protocols.
- Scalable for well plates, flasks, and larger capacity bioreactors.
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Cost-Effective
- Economical compared to similar transfection products in the market.
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Multiple Formats Available
- Available in cGMP grade and in both powder and liquid formats.
A Trusted Transfection Reagent Backed by Decades of Research
Kyfora Bio, a bioprocessing brand of Polysciences, is dedicated to providing high-quality reagents and excipients for cell and gene therapy. With over 60 years of expertise, Polysciences has been a trusted partner for pharmaceutical and biotechnology companies worldwide.
PEI MAX® has been referenced in thousands of peer-reviewed journal articles, demonstrating its effectiveness in transfection and gene delivery applications. As a leading cGMP-compliant transfection reagent, PEI MAX® continues to help revolutionize bioprocessing and therapeutic development, offering researchers a reliable and cost-effective solution for scalable gene expression and viral vector production.
| Catalog No. | 24765 |
| Appearance | White to off-white free flowing solid |
| Molecular Weight | 40,000 (~22,000 free base) |
| Solubility | Cold & room temperature water |
| Insoluble in | Common organic solvents (ethanol, acetone, tetrahydrofuran) |
| Hazards | Irritant |
| Store At | Room temperature |
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