ALC-0315 (14491)


mg: 25 mg
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Sale price$210.00
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Description

ALC-0315 is an ionizable lipid used for the delivery of mRNA in vitro and in vivo. Ionizable lipids are neutral at physiological pH but protonated at acidic pH. When protonated, ionizable lipids condense nucleic acids through electrostatic interactions and promote fusion with endosomal membranes. They can be used to formulate lipid nanoparticles (LNPs), like those used in the COVID-19 vaccine.

Applications(s): mRNA delivery, LNPs

Catalog No. 14491
CAS No. 2036272-55-4
Molecular Formula C48H95NO5
Appearance Solid
Molecular Weight 766.3 g/mol
Shipping & Handling Requirements Cold pack
Store At 4°C, protect from light

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