Description
ALC-0315 is an ionizable lipid designed for the delivery of mRNA in both in vitro and in vivo applications. This lipid is neutral at physiological pH, enabling compatibility with biological systems, but becomes protonated under acidic conditions. Upon protonation, ALC-0315 facilitates electrostatic interactions with nucleic acids and enhances endosomal escape by promoting fusion with endosomal membranes. This property makes it an essential component in lipid nanoparticle (LNP) formulations for effective mRNA delivery. This reagent is intended exclusively for research purposes.
Key Features:
- Ionizable lipid for LNP formulation
- Enhances endosomal membrane fusion for efficient delivery
Applications: mRNA delivery, LNP formulation
| CAS No. | 2036272-55-4 |
| Storage Temperature | 4°C, protect from light |
| Shipping & Handling Requirements | Cold pack |