Stigmasterol hemisuccinate (STEMS) is a pH-responsive modified version of stigmasterol, a naturally occuring plant sterol. Stigmasterol is a cholesterol derivative that is growing in the bioprocessing space for its potential to enhance mRNA transfection efficiency. Conjugation to hemiscuccinate has been shown to improve the cellular uptake in acidic microenvironments, such as those around tumors, making it a valuable tool for targeted drug delivery. STEMS is ideal for use in lipid nanoparticle (LNP) formulations aimed at improving delivery efficiency of therapeutics. For research use only.
| CAS Number | 86674-63-7 |
|---|---|
| Store At Temperature | -20°C, tightly closed in a cool, well-ventilated place |
| Shipping Condition | Dry ice |
Stigmasterol hemisuccinate (STEMS) is a pH-responsive modified version of stigmasterol, a naturally occuring plant sterol. Stigmasterol is a cholesterol derivative that is growing in the bioprocessing space for its potential to enhance mRNA transfection efficiency. Conjugation to hemiscuccinate has been shown to improve the cellular uptake in acidic microenvironments, such as those around tumors, making it a valuable tool for targeted drug delivery. STEMS is ideal for use in lipid nanoparticle (LNP) formulations aimed at improving delivery efficiency of therapeutics. For research use only.
| CAS Number | 86674-63-7 |
|---|---|
| Store At Temperature | -20°C, tightly closed in a cool, well-ventilated place |
| Shipping Condition | Dry ice |