beta-sitosterol hemisuccinate (β-STEMS) (14401)

β-Sitosterol Hemisuccinate (β-STEMS)is a pH-responsive derivative of β-sitosterol, a naturally occurring plant sterol. This modified sterol is gaining attention in bioprocessing for its potential to enhance mRNA transfection efficiency. The hemisuccinate conjugation promotes cellular uptake, particularly in acidic microenvironments, making it a valuable tool for targeted drug delivery, especially in areas with low pH, such as tumor sites. β-STEMS is ideal for use in lipid nanoparticle (LNP) formulations aimed at improving delivery efficiency in challenging cellular contexts. For research use only.

Applications: Cellular uptake, lipid nanoparticles (LNPs), targeted drug delivery